Novel Conjugate of Moxifloxacin and Carboxymethylated Glucan with Enhanced Activity against Mycobacterium tuberculosis

Mycobacterium tuberculosis is an intracellular pathogen that persists within macrophages of the human host. One approach to improving the treatment of tuberculosis (TB) is the targeted delivery of antibiotics to macrophages using ligands to macrophage receptors. The moxifloxacin-conjugated dansylate...

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Detalhes bibliográficos
Main Authors: Schwartz, Y. S., Dushkin, M. I., Vavilin, V. A., Melnikova, E. V., Khoschenko, O. M., Kozlov, V. A., Agafonov, A. P., Alekseev, A. Y., Rassadkin, Y., Shestapalov, A. M., Azaev, M. S., Saraev, D. V., Filimonov, P. N., Kurunov, Y., Svistelnik, A. V., Krasnov, V. A., Pathak, A., Derrick, S. C., Reynolds, R. C., Morris, S., Blinov, V. M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1479142/
https://ncbi.nlm.nih.gov/pubmed/16723555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00362-05
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