Novel Conjugate of Moxifloxacin and Carboxymethylated Glucan with Enhanced Activity against Mycobacterium tuberculosis

Mycobacterium tuberculosis is an intracellular pathogen that persists within macrophages of the human host. One approach to improving the treatment of tuberculosis (TB) is the targeted delivery of antibiotics to macrophages using ligands to macrophage receptors. The moxifloxacin-conjugated dansylate...

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Autores principales: Schwartz, Y. S., Dushkin, M. I., Vavilin, V. A., Melnikova, E. V., Khoschenko, O. M., Kozlov, V. A., Agafonov, A. P., Alekseev, A. Y., Rassadkin, Y., Shestapalov, A. M., Azaev, M. S., Saraev, D. V., Filimonov, P. N., Kurunov, Y., Svistelnik, A. V., Krasnov, V. A., Pathak, A., Derrick, S. C., Reynolds, R. C., Morris, S., Blinov, V. M.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2006
Materias:
Experimental Therapeutics
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1479142/
https://ncbi.nlm.nih.gov/pubmed/16723555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00362-05
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