Novel Conjugate of Moxifloxacin and Carboxymethylated Glucan with Enhanced Activity against Mycobacterium tuberculosis

Mycobacterium tuberculosis is an intracellular pathogen that persists within macrophages of the human host. One approach to improving the treatment of tuberculosis (TB) is the targeted delivery of antibiotics to macrophages using ligands to macrophage receptors. The moxifloxacin-conjugated dansylate...

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Hlavní autoři: Schwartz, Y. S., Dushkin, M. I., Vavilin, V. A., Melnikova, E. V., Khoschenko, O. M., Kozlov, V. A., Agafonov, A. P., Alekseev, A. Y., Rassadkin, Y., Shestapalov, A. M., Azaev, M. S., Saraev, D. V., Filimonov, P. N., Kurunov, Y., Svistelnik, A. V., Krasnov, V. A., Pathak, A., Derrick, S. C., Reynolds, R. C., Morris, S., Blinov, V. M.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2006
Témata:
Experimental Therapeutics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1479142/
https://ncbi.nlm.nih.gov/pubmed/16723555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00362-05
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