High-dose rifampicin kills persisters, shortens treatment duration, and reduces relapse rate in vitro and in vivo

Por Hu, Yanmin, Liu, Alexander, Ortega-Muro, Fatima, Alameda-Martin, Laura, Mitchison, Denis, Coates, Anthony
Publicado no Front Microbiol (2015)

Investigation of Elimination Rate, Persistent Subpopulation Removal, and Relapse Rates of Mycobacterium tuberculosis by Using Combinations of First-Line Drugs in a Modified Cornell...

Por Hu, Yanmin, Pertinez, Henry, Ortega-Muro, Fatima, Alameda-Martin, Laura, Liu, Yingjun, Schipani, Alessandro, Davies, Geraint, Coates, Anthony
Publicado no Antimicrob Agents Chemother (2016)

Inhibiting mycobacterial tryptophan synthase by targeting the inter-subunit interface

Por Abrahams, Katherine A., Cox, Jonathan A. G., Fütterer, Klaus, Rullas, Joaquín, Ortega-Muro, Fátima, Loman, Nicholas J., Moynihan, Patrick J., Pérez-Herrán, Esther, Jiménez, Elena, Esquivias, Jorge, Barros, David, Ballell, Lluís, Alemparte, Carlos, Besra, Gurdyal S.
Publicado no Sci Rep (2017)

Tetrahydropyrazolo[1,5-a]Pyrimidine-3-Carboxamide and N-Benzyl-6′,7′-Dihydrospiro[Piperidine-4,4′-Thieno[3,2-c]Pyran] Analogues with Bactericidal Efficacy against Mycobacterium tub...

Por Remuiñán, Modesto J., Pérez-Herrán, Esther, Rullás, Joaquín, Alemparte, Carlos, Martínez-Hoyos, María, Dow, David J., Afari, Johnson, Mehta, Nalini, Esquivias, Jorge, Jiménez, Elena, Ortega-Muro, Fátima, Fraile-Gabaldón, María Teresa, Spivey, Vickey L., Loman, Nicholas J., Pallen, Mark J., Constantinidou, Chrystala, Minick, Douglas J., Cacho, Mónica, Rebollo-López, María José, González, Carolina, Sousa, Verónica, Angulo-Barturen, Iñigo, Mendoza-Losana, Alfonso, Barros, David, Besra, Gurdyal S., Ballell, Lluís, Cammack, Nicholas
Publicado em 2013