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Thiopurine S-methyltransferase testing for averting drug toxicity: a meta-analysis of diagnostic test accuracy
Thiopurine S-methyltransferase (TPMT) deficiency increases the risk of serious adverse events in persons receiving thiopurines. The objective was to synthesize reported sensitivity and specificity of TPMT phenotyping and genotyping using a latent class hierarchical summary receiver operating charact...
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| Publicado en: | Pharmacogenomics J |
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| Autores principales: | , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2016
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4957983/ https://ncbi.nlm.nih.gov/pubmed/27217052 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tpj.2016.37 |
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