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Thiopurine S-methyltransferase testing for averting drug toxicity in patients receiving thiopurines: a systematic review

AIM: Thiopurine S-methyltransferase (TPMT) testing is used in patients receiving thiopurines to identify enzyme deficiencies and risk for adverse drug reactions. It is uncertain whether genotyping is superior to phenotyping. The objectives were to conduct a systematic review of TPMT-test performance...

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Detalhes bibliográficos
Publicado no:Pharmacogenomics
Main Authors: Roy, Lilla M, Zur, Richard M, Uleryk, Elizabeth, Carew, Chris, Ito, Shinya, Ungar, Wendy J
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4931919/
https://ncbi.nlm.nih.gov/pubmed/27020704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/pgs.16.12
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