Negative control of CSL gene transcription by stress/DNA damage response and p53

CSL is a key transcriptional repressor and mediator of Notch signaling. Despite wide interest in CSL, mechanisms responsible for its own regulation are little studied. CSL down-modulation in human dermal fibroblasts (HDFs) leads to conversion into cancer associated fibroblasts (CAF), promoting kerat...

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Publicado en:Cell Cycle
Autores principales: Menietti, Elena, Xu, Xiaoying, Ostano, Paola, Joseph, Jean-Marc, Lefort, Karine, Dotto, G. Paolo
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 2016
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Reports
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4957600/
https://ncbi.nlm.nih.gov/pubmed/27163456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2016.1186317
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