Combinatorial epigenetic therapy in diffuse large B cell lymphoma pre-clinical models and patients

BACKGROUND: Refractory and/or relapsed diffuse large B cell lymphoma (RR-DLBCL) patients are incurable with conventional chemotherapy due to the aggressiveness and the chemorefractory state of these tumors. DNA hypermethylation and histone deacetylation are two major epigenetic modifications by whic...

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Bibliografiske detaljer
Udgivet i:Clin Epigenetics
Main Authors: Pera, Benet, Tang, Tiffany, Marullo, Rossella, Yang, Shao-Ning, Ahn, Haelee, Patel, Jayeshkumar, Elstrom, Rebecca, Ruan, Jia, Furman, Richard, Leonard, John, Cerchietti, Leandro, Martin, Peter
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2016
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4957280/
https://ncbi.nlm.nih.gov/pubmed/27453763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-016-0245-y
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