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Therapeutic implication of concomitant chromosomal aberrations in patients with aggressive B-cell lymphomas

A subset of diffuse large B-cell lymphomas (DLBCL) harbors concomitant rearrangements of MYC, BCL2 and BCL6 and is characterized by clinical aggressiveness and intrinsic refractoriness to standard chemo-immunotherapy. Commonly identified as “double or triple hit” lymphomas, these diseases represent...

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Detalhes bibliográficos
Publicado no:Cell Cycle
Main Authors: Marullo, Rossella, Rutherford, Sarah C., Leonard, John P., Cerchietti, Leandro
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5004704/
https://ncbi.nlm.nih.gov/pubmed/27419806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2016.1207839
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