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Multiple Quality Control Pathways Limit Non-protein Amino Acid Use by Yeast Cytoplasmic Phenylalanyl-tRNA Synthetase

Non-protein amino acids, particularly isomers of the proteinogenic amino acids, present a threat to proteome integrity if they are mistakenly inserted into proteins. Quality control during aminoacyl-tRNA synthesis reduces non-protein amino acid incorporation by both substrate discrimination and proo...

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Publicado en:J Biol Chem
Main Authors: Moghal, Adil, Hwang, Lin, Faull, Kym, Ibba, Michael
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4957061/
https://ncbi.nlm.nih.gov/pubmed/27226603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.726828
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