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Evolutionary Basis of Converting a Bacterial tRNA Synthetase into a Yeast Cytoplasmic or Mitochondrial Enzyme

Previous studies showed that cytoplasmic and mitochondrial forms of yeast valyl-tRNA synthetase (ValRS) are specified by the VAS1 gene through alternative initiation of translation. Sequence comparison suggests that the yeast cytoplasmic (or mature mitochondrial) ValRS contains an N-terminal appenda...

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Detalhes bibliográficos
Main Authors: Chiu, Wen-Chih, Chang, Chia-Pei, Wang, Chien-Chia
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2781989/
https://ncbi.nlm.nih.gov/pubmed/19574213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.031047
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