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Molecular insights into cell toxicity of a novel familial amyloidogenic variant of β2‐microglobulin
The first genetic variant of β(2)‐microglobulin (b2M) associated with a familial form of systemic amyloidosis has been recently described. The mutated protein, carrying a substitution of Asp at position 76 with an Asn (D76N b2M), exhibits a strongly enhanced amyloidogenic tendency to aggregate with...
Zapisane w:
| Wydane w: | J Cell Mol Med |
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| Główni autorzy: | , , , , , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
John Wiley and Sons Inc.
2016
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4956941/ https://ncbi.nlm.nih.gov/pubmed/26990223 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12833 |
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