Molecular insights into cell toxicity of a novel familial amyloidogenic variant of β2‐microglobulin

The first genetic variant of β(2)‐microglobulin (b2M) associated with a familial form of systemic amyloidosis has been recently described. The mutated protein, carrying a substitution of Asp at position 76 with an Asn (D76N b2M), exhibits a strongly enhanced amyloidogenic tendency to aggregate with...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:J Cell Mol Med
Hauptverfasser: Leri, Manuela, Bemporad, Francesco, Oropesa‐Nuñez, Reinier, Canale, Claudio, Calamai, Martino, Nosi, Daniele, Ramazzotti, Matteo, Giorgetti, Sofia, Pavone, Francesco S., Bellotti, Vittorio, Stefani, Massimo, Bucciantini, Monica
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2016
Schlagworte:
Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4956941/
https://ncbi.nlm.nih.gov/pubmed/26990223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12833
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge