Molecular Mechanisms for Drug Hypersensitivity Induced by the Malaria Parasite’s Chloroquine Resistance Transporter

Mutations in the Plasmodium falciparum ‘chloroquine resistance transporter’ (PfCRT) confer resistance to chloroquine (CQ) and related antimalarials by enabling the protein to transport these drugs away from their targets within the parasite’s digestive vacuole (DV). However, CQ resistance-conferring...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:PLoS Pathog
Main Authors: Richards, Sashika N., Nash, Megan N., Baker, Eileen S., Webster, Michael W., Lehane, Adele M., Shafik, Sarah H., Martin, Rowena E.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2016
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4956231/
https://ncbi.nlm.nih.gov/pubmed/27441371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005725
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares