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Molecular Mechanisms for Drug Hypersensitivity Induced by the Malaria Parasite’s Chloroquine Resistance Transporter

Mutations in the Plasmodium falciparum ‘chloroquine resistance transporter’ (PfCRT) confer resistance to chloroquine (CQ) and related antimalarials by enabling the protein to transport these drugs away from their targets within the parasite’s digestive vacuole (DV). However, CQ resistance-conferring...

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Detaylı Bibliyografya
Yayımlandı:PLoS Pathog
Asıl Yazarlar: Richards, Sashika N., Nash, Megan N., Baker, Eileen S., Webster, Michael W., Lehane, Adele M., Shafik, Sarah H., Martin, Rowena E.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2016
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4956231/
https://ncbi.nlm.nih.gov/pubmed/27441371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005725
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