Drug binding to higher ordered DNA structures: netropsin complexation with a nucleic acid triple helix.
We have used a combination of spectroscopic and calorimetric techniques to characterize how netropsin, a ligand that binds in the minor groove of DNA, influences the properties of a DNA triple helix. Specifically, our data allow us to reach the following conclusions: (i) netropsin binds to the tripl...
Uloženo v:
| Vydáno v: | Proc Natl Acad Sci U S A |
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| Hlavní autoři: | , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
1992
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC49560/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1321445/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.14.6653 |
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