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Drug binding to higher ordered DNA structures: netropsin complexation with a nucleic acid triple helix.

We have used a combination of spectroscopic and calorimetric techniques to characterize how netropsin, a ligand that binds in the minor groove of DNA, influences the properties of a DNA triple helix. Specifically, our data allow us to reach the following conclusions: (i) netropsin binds to the tripl...

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Bibliografski detalji
Glavni autori: Park, Y W, Breslauer, K J
Format: Artigo
Jezik:Inglês
Izdano: 1992
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC49560/
https://ncbi.nlm.nih.gov/pubmed/1321445
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