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Calorimetric and spectroscopic investigation of drug--DNA interactions: II. Dipyrandium binding to poly d(AT).

We report the first calorimetric investigation of steroid diamine binding to a DNA duplex. Absorption spectroscopy, batch calorimetry, and differential scanning calorimetry (DSC) have been used to detect, monitor, and thermodynamically characterize the binding of the steroid diamine, dipyrandium, to...

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Detalhes bibliográficos
Main Authors: Marky, L A, Snyder, J G, Breslauer, K J
Formato: Artigo
Idioma:Inglês
Publicado em: 1983
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC326308/
https://ncbi.nlm.nih.gov/pubmed/6889134
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