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Drug binding to higher ordered DNA structures: netropsin complexation with a nucleic acid triple helix.

We have used a combination of spectroscopic and calorimetric techniques to characterize how netropsin, a ligand that binds in the minor groove of DNA, influences the properties of a DNA triple helix. Specifically, our data allow us to reach the following conclusions: (i) netropsin binds to the tripl...

Täydet tiedot

Tallennettuna:
Julkaisussa:Proc Natl Acad Sci U S A
Päätekijät: Park, Y W, Breslauer, K J
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 1992
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC49560/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1321445/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.14.6653
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