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Probing the minimal determinants of zinc binding with computational protein design

Structure-based protein design tests our understanding of the minimal determinants of protein structure and function. Previous studies have demonstrated that placing zinc binding amino acids (His, Glu, Asp or Cys) near each other in a folded protein in an arrangement predicted to be tetrahedral is o...

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Bibliografiske detaljer
Udgivet i:Protein Eng Des Sel
Main Authors: Guffy, Sharon L., Der, Bryan S., Kuhlman, Brian
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4955873/
https://ncbi.nlm.nih.gov/pubmed/27358168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/protein/gzw026
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