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Probing the DNA-Binding Affinity and Specificity of Designed Zinc Finger Proteins
Engineered transcription factors and endonucleases based on designed Cys(2)His(2) zinc finger domains have proven to be effective tools for the directed regulation and modification of genes. The introduction of this technology into both research and clinical settings necessitates the development of...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
The Biophysical Society
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2830443/ https://ncbi.nlm.nih.gov/pubmed/20197039 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.11.021 |
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