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Probing the DNA-Binding Affinity and Specificity of Designed Zinc Finger Proteins

Engineered transcription factors and endonucleases based on designed Cys(2)His(2) zinc finger domains have proven to be effective tools for the directed regulation and modification of genes. The introduction of this technology into both research and clinical settings necessitates the development of...

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Bibliografske podrobnosti
Main Authors: Jantz, Derek, Berg, Jeremy M.
Format: Artigo
Jezik:Inglês
Izdano: The Biophysical Society 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2830443/
https://ncbi.nlm.nih.gov/pubmed/20197039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.11.021
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