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Arabinoamidine synthesis and its inhibition toward-glucosidase (sweet almonds) in comparison to a library of galactonoamidines

Aiming at the development of potent inhibitors of -glucosidases, a small library of galactonoamidines and one arabinoamidine derived in analogy were studied as inhibitors of sweet almond -glucosidase. The five-membered glycon in arabinoamidine was shown to interact with the proton donor in the activ...

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Detalles Bibliográficos
Publicado en:Bioorg Med Chem
Main Authors: Pickens, Jessica B., Striegler, Susanne, Fan, Qiu-Hua
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4955783/
https://ncbi.nlm.nih.gov/pubmed/27298003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2016.04.069
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