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Illuminating the binding interactions of galactonoamidines during the inhibition of β-galactosidase (E. coli)

Several galactonoamidines were previously identified as very potent competitive inhibitors that exhibit stabilizing hydrophobic interactions of the aglycon in the active site of β-galactosidase (A. oryzae). To elucidate the contributions of the glycon to the overall inhibition ability of the compoun...

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Detalhes bibliográficos
Publicado no:Bioorg Med Chem
Main Authors: Fan, Qiu-Hua, Pickens, Jessica B., Striegler, Susanne, Gervaise, Cédric D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4738082/
https://ncbi.nlm.nih.gov/pubmed/26740154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2015.12.034
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