Practical Immunoaffinity-Enrichment LC-MS for Measuring Protein Kinetics of Low-Abundance Proteins

BACKGROUND: For a more complete understanding of pharmacodynamic, metabolic, and pathophysiologic effects, protein kinetics, such as production rate and fractional catabolic rate, can offer substantially more information than protein concentration alone. Kinetic experiments with stable isotope trace...

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Publicat a:Clin Chem
Autors principals: Lassman, Michael E., McAvoy, Thomas, Lee, Anita Y.H., Chappell, Derek, Wong, Oitak, Zhou, Haihong, Reyes-Soffer, Gissette, Ginsberg, Henry N., Millar, John S., Rader, Daniel J., Gutstein, David E., Laterza, Omar
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4955776/
https://ncbi.nlm.nih.gov/pubmed/24751376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1373/clinchem.2014.222455
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