Static and turnover kinetic measurement of protein biomarkers involved in triglyceride metabolism including apoB48 and apoA5 by LC/MS/MS

LC/MS quantification of multiple plasma proteins that differ by several orders of magnitude in concentration from a single sample is challenging. We present a strategy that allows the simultaneous determination of the concentration and turnover kinetics of higher and lower abundant proteins from a s...

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Bibliografiske detaljer
Main Authors: Pan, Yi, Zhou, Haihong, Mahsut, Ablatt, Rohm, Rory J., Berejnaia, Olga, Price, Olga, Chen, Ying, Castro-Perez, Jose, Lassman, Michael E., McLaren, David, Conway, James, Jensen, Kristian K., Thomas, Tiffany, Reyes-Soffer, Gissette, Ginsberg, Henry N., Gutstein, David E., Cleary, Michele, Previs, Stephen F., Roddy, Thomas P.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Biochemistry and Molecular Biology 2014
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Methods
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4031949/
https://ncbi.nlm.nih.gov/pubmed/24694356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.D047829
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