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Replacing immunoassays with tryptic digestion-peptide immunoaffinity enrichment and LC–MS/MS

For decades, immunoassays have provided the framework for protein biomarker studies in clinical medicine and in therapeutic monitoring for drug development. At the same time, investigators have uncovered many issues that make immunoassays unreliable in many human serum and plasma samples. LC-MS/MS a...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Becker, Jessica O, Hoofnagle, Andrew N
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3699856/
https://ncbi.nlm.nih.gov/pubmed/22303832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/bio.11.319
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