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Optimization of Tryptic Digestion Methods for LC-MS/MS Analysis of Chimeric Immunoglobulin G

Liquid chromatography- tandem mass spectrometry (LC-MS/MS) is an important tool in characterizing the amino acid sequence and post-translational modifications of therapeutic antibodies. Identifying changes in the antibody is important in monitoring possible changes in activity and/or immunogenicity....

詳細記述

保存先:
書誌詳細
主要な著者: Yan, X., Tchekhovskoi, D., Mirokhin, Y., Stein, S., Kilpatrick, Lisa
フォーマット: Artigo
言語:Inglês
出版事項: Association of Biomolecular Resource Facilities 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3630693/
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