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Optimization of Tryptic Digestion Methods for LC-MS/MS Analysis of Chimeric Immunoglobulin G
Liquid chromatography- tandem mass spectrometry (LC-MS/MS) is an important tool in characterizing the amino acid sequence and post-translational modifications of therapeutic antibodies. Identifying changes in the antibody is important in monitoring possible changes in activity and/or immunogenicity....
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Association of Biomolecular Resource Facilities
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3630693/ |
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