Practical Immunoaffinity-Enrichment LC-MS for Measuring Protein Kinetics of Low-Abundance Proteins

BACKGROUND: For a more complete understanding of pharmacodynamic, metabolic, and pathophysiologic effects, protein kinetics, such as production rate and fractional catabolic rate, can offer substantially more information than protein concentration alone. Kinetic experiments with stable isotope trace...

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Detalhes bibliográficos
Publicado no:Clin Chem
Main Authors: Lassman, Michael E., McAvoy, Thomas, Lee, Anita Y.H., Chappell, Derek, Wong, Oitak, Zhou, Haihong, Reyes-Soffer, Gissette, Ginsberg, Henry N., Millar, John S., Rader, Daniel J., Gutstein, David E., Laterza, Omar
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4955776/
https://ncbi.nlm.nih.gov/pubmed/24751376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1373/clinchem.2014.222455
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