Practical Immunoaffinity-Enrichment LC-MS for Measuring Protein Kinetics of Low-Abundance Proteins

BACKGROUND: For a more complete understanding of pharmacodynamic, metabolic, and pathophysiologic effects, protein kinetics, such as production rate and fractional catabolic rate, can offer substantially more information than protein concentration alone. Kinetic experiments with stable isotope trace...

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Pubblicato in:Clin Chem
Autori principali: Lassman, Michael E., McAvoy, Thomas, Lee, Anita Y.H., Chappell, Derek, Wong, Oitak, Zhou, Haihong, Reyes-Soffer, Gissette, Ginsberg, Henry N., Millar, John S., Rader, Daniel J., Gutstein, David E., Laterza, Omar
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4955776/
https://ncbi.nlm.nih.gov/pubmed/24751376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1373/clinchem.2014.222455
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