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cFLIP(L) interrupts IRF3-CBP-DNA interactions to inhibit IRF3-driven transcription

Type I interferon (IFN) induction is critical for anti-viral and anti-cancer defenses. Proper down-regulation of type I IFN is equally important to avoid deleterious imbalances in the immune response. The cellular FLIP long isoform protein (cFLIP(L)) controls type I IFN production, but opposing publ...

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Xehetasun bibliografikoak
Argitaratua izan da:J Immunol
Egile Nagusiak: Gates, Lauren T., Shisler, Joanna L.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4955763/
https://ncbi.nlm.nih.gov/pubmed/27342840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1502611
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