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When alcohol is the answer: trapping, identifying and quantifying simple alkylating species in aqueous environments

Alkylating agents are a significant class of environmental carcinogens as well as commonly used anticancer therapeutics. Traditional alkylating activity assays have utilized the colorimetric reagent 4-(4-nitrobenzyl)pyridine (4NBP). However, 4NBP based assays have a relatively low sensitivity toward...

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Detalhes bibliográficos
Publicado no:Anal Biochem
Main Authors: Penketh, P. G., Shyam, K., Baumann, R. P, Zhu, Rui, Ishiguro, K., Sartorelli, A. C., Ratner, E. S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4955734/
https://ncbi.nlm.nih.gov/pubmed/27188264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2016.04.020
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