Embryonic stem cells induce pluripotency in somatic cell fusion through biphasic reprogramming

It is a long-held paradigm that cell fusion reprograms gene expression, but the extent of reprogramming and whether it is affected by the cell types employed remain unknown. We recently showed that the silencing of somatic genes is attributable to either trans-acting cellular environment or cis-acti...

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Detalhes bibliográficos
Publicado no:Mol Cell
Main Authors: Foshay, Kara M., Looney, Timothy J., Chari, Sheila, Mao, Frank Fuxiang, Lee, Jae Hyun, Zhang, Li, Fernandes, Croydon J., Baker, Samuel W., Clift, Kayla L., Gaetz, Jedidiah, Di, Chun-Guang, Xiang, Andy Peng, Lahn, Bruce T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4955287/
https://ncbi.nlm.nih.gov/pubmed/22445485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2012.02.013
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