Embryonic stem cells induce pluripotency in somatic cell fusion through biphasic reprogramming

It is a long-held paradigm that cell fusion reprograms gene expression, but the extent of reprogramming and whether it is affected by the cell types employed remain unknown. We recently showed that the silencing of somatic genes is attributable to either trans-acting cellular environment or cis-acti...

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Veröffentlicht in:Mol Cell
Hauptverfasser: Foshay, Kara M., Looney, Timothy J., Chari, Sheila, Mao, Frank Fuxiang, Lee, Jae Hyun, Zhang, Li, Fernandes, Croydon J., Baker, Samuel W., Clift, Kayla L., Gaetz, Jedidiah, Di, Chun-Guang, Xiang, Andy Peng, Lahn, Bruce T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4955287/
https://ncbi.nlm.nih.gov/pubmed/22445485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2012.02.013
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