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Evidence for a critical role of gene occlusion in cell fate restriction
The progressive restriction of cell fate during lineage differentiation is a poorly understood phenomenon despite its ubiquity in multicellular organisms. We recently used a cell fusion assay to define a mode of epigenetic silencing that we termed “occlusion”, wherein affected genes are silenced by...
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| Main Authors: | , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3297702/ https://ncbi.nlm.nih.gov/pubmed/22124232 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2011.190 |
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