Evidence for a critical role of gene occlusion in cell fate restriction

The progressive restriction of cell fate during lineage differentiation is a poorly understood phenomenon despite its ubiquity in multicellular organisms. We recently used a cell fusion assay to define a mode of epigenetic silencing that we termed “occlusion”, wherein affected genes are silenced by...

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Autors principals: Gaetz, Jedidiah, Clift, Kayla L, Fernandes, Croydon J, Mao, Frank Fuxiang, Lee, Jae Hyun, Zhang, Li, Baker, Samuel W, Looney, Timothy J, Foshay, Kara M, Yu, Wei-Hua, Xiang, Andy Peng, Lahn, Bruce T
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2012
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3297702/
https://ncbi.nlm.nih.gov/pubmed/22124232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2011.190
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