Cell-Specific Promoters Enable Lipid-Based Nanoparticles to Deliver Genes to Specific Cells of the Retina In Vivo

Non-viral vectors, such as lipid-based nanoparticles (liposome-protamine-DNA complex [LPD]), could be used to deliver a functional gene to the retina to correct visual function and treat blindness. However, one of the limitations of LPD is the lack of cell specificity, as the retina is composed of s...

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Detalles Bibliográficos
Publicado en:Theranostics
Autores principales: Wang, Yuhong, Rajala, Ammaji, Cao, Binrui, Ranjo-Bishop, Michelle, Agbaga, Martin-Paul, Mao, Chuanbin, Rajala, Raju V.S.
Formato: Artigo
Lenguaje:Inglês
Publicado: Ivyspring International Publisher 2016
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Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4955052/
https://ncbi.nlm.nih.gov/pubmed/27446487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.15230
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