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Cell-Specific Promoters Enable Lipid-Based Nanoparticles to Deliver Genes to Specific Cells of the Retina In Vivo

Non-viral vectors, such as lipid-based nanoparticles (liposome-protamine-DNA complex [LPD]), could be used to deliver a functional gene to the retina to correct visual function and treat blindness. However, one of the limitations of LPD is the lack of cell specificity, as the retina is composed of s...

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Detalhes bibliográficos
Publicado no:Theranostics
Main Authors: Wang, Yuhong, Rajala, Ammaji, Cao, Binrui, Ranjo-Bishop, Michelle, Agbaga, Martin-Paul, Mao, Chuanbin, Rajala, Raju V.S.
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4955052/
https://ncbi.nlm.nih.gov/pubmed/27446487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.15230
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