Cell-Specific Promoters Enable Lipid-Based Nanoparticles to Deliver Genes to Specific Cells of the Retina In Vivo

Non-viral vectors, such as lipid-based nanoparticles (liposome-protamine-DNA complex [LPD]), could be used to deliver a functional gene to the retina to correct visual function and treat blindness. However, one of the limitations of LPD is the lack of cell specificity, as the retina is composed of s...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Theranostics
Prif Awduron: Wang, Yuhong, Rajala, Ammaji, Cao, Binrui, Ranjo-Bishop, Michelle, Agbaga, Martin-Paul, Mao, Chuanbin, Rajala, Raju V.S.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Ivyspring International Publisher 2016
Pynciau:
Research Paper
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4955052/
https://ncbi.nlm.nih.gov/pubmed/27446487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.15230
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