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The Molecular Mechanism of Opening the Helix Bundle Crossing (HBC) Gate of a Kir Channel

Inwardly rectifying K(+) (Kir) channels, serving as natural molecular nanomachines, transport potassium ions across the plasma membrane of the cell. Along the ion permeation pathway, three relatively narrow regions (the selectivity filter (SF), the inner helix bundle crossing (HBC), and the cytosoli...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Meng, Xuan-Yu, Liu, Shengtang, Cui, Meng, Zhou, Ruhong, Logothetis, Diomedes E.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4954981/
https://ncbi.nlm.nih.gov/pubmed/27439597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep29399
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