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The Molecular Mechanism of Opening the Helix Bundle Crossing (HBC) Gate of a Kir Channel

Inwardly rectifying K(+) (Kir) channels, serving as natural molecular nanomachines, transport potassium ions across the plasma membrane of the cell. Along the ion permeation pathway, three relatively narrow regions (the selectivity filter (SF), the inner helix bundle crossing (HBC), and the cytosoli...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Meng, Xuan-Yu, Liu, Shengtang, Cui, Meng, Zhou, Ruhong, Logothetis, Diomedes E.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4954981/
https://ncbi.nlm.nih.gov/pubmed/27439597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep29399
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