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Mutant bacterial sodium channels as models for local anesthetic block of eukaryotic proteins
Voltage gated sodium channels are the target of a range of local anesthetic, anti-epileptic and anti-arrhythmic compounds. But, gaining a molecular level understanding of their mode of action is difficult as we only have atomic resolution structures of bacterial sodium channels not their eukaryotic...
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| Publicado no: | Channels (Austin) |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4954582/ https://ncbi.nlm.nih.gov/pubmed/26852716 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19336950.2016.1148224 |
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