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Local anesthetic inhibition of a bacterial sodium channel

Recent structural breakthroughs with the voltage-gated sodium channel from Arcobacter butzleri suggest that such bacterial channels may provide a structural platform to advance the understanding of eukaryotic sodium channel gating and pharmacology. We therefore set out to determine whether compounds...

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Autores principales: Lee, Sora, Goodchild, Samuel J., Ahern, Christopher A.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3362524/
https://ncbi.nlm.nih.gov/pubmed/22641643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201210779
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