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State-Dependent Inhibition of Sodium Channels by Local Anesthetics: A 40-Year Evolution()

Knowledge about the mechanism of impulse blockade by local anesthetics has evolved over the past four decades, from the realization that Na(+) channels were inhibited to affect the impulse blockade to an identification of the amino acid residues within the Na(+) channel that bind the local anestheti...

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Main Authors: Wang, G.-K., Strichartz, G. R.
格式: Artigo
語言:Inglês
出版: 2012
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3660973/
https://ncbi.nlm.nih.gov/pubmed/23710324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1134/S1990747812010151
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