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Molecular and functional determinants of local anesthetic inhibition of NaChBac
In our recent publication, we describe the local anesthetic (LA) inhibition of the prokaryotic voltage gated sodium channel NaChBac. Despite the numerous functional and putative structural differences with the mammalian sodium channels, the data show that LA compounds effectively and reversibly inhi...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3508782/ https://ncbi.nlm.nih.gov/pubmed/22992485 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/chan.21807 |
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