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Propofol inhibits the voltage-gated sodium channel NaChBac at multiple sites
Voltage-gated sodium (Na(V)) channels are important targets of general anesthetics, including the intravenous anesthetic propofol. Electrophysiology studies on the prokaryotic Na(V) channel NaChBac have demonstrated that propofol promotes channel activation and accelerates activation-coupled inactiv...
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| Foilsithe in: | J Gen Physiol |
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| Main Authors: | , , , , , , , , , , , , |
| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
Rockefeller University Press
2018
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6122922/ https://ncbi.nlm.nih.gov/pubmed/30018039 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201811993 |
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