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Local anesthetic block of sodium channels in normal and pronase-treated squid giant axons.

The inhibition of sodium currents by local anesthetics and other blocking compounds was studied in perfused, voltage-clamped segments of squid giant axon. When applied internally, each of the eight compounds studied results in accumulating "use-depnedent" block of sodium currents upon repe...

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Detalhes bibliográficos
Autor principal: Cahalan, M D
Formato: Artigo
Idioma:Inglês
Publicado em: 1978
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1473517/
https://ncbi.nlm.nih.gov/pubmed/687766
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