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Block of sodium conductance and gating current in squid giant axons poisoned with quaternary strychnine.

Quaternary strychnine blocks sodium channels from the axoplasmic side, probably by insertion into the inner channel mouth. Block is strongly voltage dependent, being more pronounced in depolarized than in resting axons. Using potential steps as a means to modulate the level of block, we investigate...

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Detalles Bibliográficos
Main Authors: Cahalan, M D, Almers, W
Formato: Artigo
Idioma:Inglês
Publicado: 1979
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1328547/
https://ncbi.nlm.nih.gov/pubmed/233569
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