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Block of sodium conductance and gating current in squid giant axons poisoned with quaternary strychnine.

Quaternary strychnine blocks sodium channels from the axoplasmic side, probably by insertion into the inner channel mouth. Block is strongly voltage dependent, being more pronounced in depolarized than in resting axons. Using potential steps as a means to modulate the level of block, we investigate...

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Détails bibliographiques
Auteurs principaux: Cahalan, M D, Almers, W
Format: Artigo
Langue:Inglês
Publié: 1979
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1328547/
https://ncbi.nlm.nih.gov/pubmed/233569
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