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Diphenylhydantoin Inhibition of Sodium Conductance in Squid Giant Axon
Diphenylhydantoin, in concentration of 5-50 μM, decreases the early, transient (sodium) currents of voltage-clamped squid giant axons. These effects are dose-dependent and largely reversible. It appears that diphenylhydantoin reduces the number of open, early, transient (sodium) channels.
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
1972
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC426796/ https://ncbi.nlm.nih.gov/pubmed/4505652 |
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