Loading...

Diphenylhydantoin Inhibition of Sodium Conductance in Squid Giant Axon

Diphenylhydantoin, in concentration of 5-50 μM, decreases the early, transient (sodium) currents of voltage-clamped squid giant axons. These effects are dose-dependent and largely reversible. It appears that diphenylhydantoin reduces the number of open, early, transient (sodium) channels.

Na minha lista:
Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Lipicky, Raymond J., Gilbert, Daniel L., Stillman, Irving M.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1972
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC426796/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4505652/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.69.7.1758
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!