Transformation of the tumour microenvironment by a CD40 agonist antibody correlates with improved responses to PD-L1 blockade in a mouse orthotopic pancreatic tumour model

Despite the availability of recently developed chemotherapy regimens, survival times for pancreatic cancer patients remain poor. These patients also respond poorly to immune checkpoint blockade therapies (anti-CTLA-4, anti-PD-L1, anti-PD-1), which suggests the presence of additional immunosuppressiv...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Oncotarget
Κύριοι συγγραφείς: Luheshi, Nadia M., Coates-Ulrichsen, Jane, Harper, James, Mullins, Stefanie, Sulikowski, Michal G., Martin, Philip, Brown, Lee, Lewis, Arthur, Davies, Gareth, Morrow, Michelle, Wilkinson, Robert W.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Impact Journals LLC 2016
Θέματα:
Research Paper
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4951305/
https://ncbi.nlm.nih.gov/pubmed/26918344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7610
Ετικέτες: Προσθήκη ετικέτας
Δεν υπάρχουν, Καταχωρήστε ετικέτα πρώτοι!

Παρόμοια τεκμήρια