Gegen Qinlian decoction enhances the effect of PD-1 blockade in colorectal cancer with microsatellite stability by remodelling the gut microbiota and the tumour microenvironment

Therapeutic antibodies targeting PD-1 have made major breakthroughs in cancer treatment. However, the majority of colorectal cancer (CRC) cases are microsatellite stable (MSS) and do not respond to anti-PD-1-based immunotherapy. Combination therapy will be an ideal strategy to overcome this limitati...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Death Dis
Prif Awduron: Lv, Ji, Jia, Yitao, Li, Jing, Kuai, Wentao, Li, Yang, Guo, Fang, Xu, Xinjian, Zhao, Zhaolong, Lv, Jian, Li, Zhongxin
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2019
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6538740/
https://ncbi.nlm.nih.gov/pubmed/31138779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1638-6
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