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Preclinical evaluation of biomarkers associated with antitumor activity of MELK inhibitor
MELK is upregulated in various types of human cancer and is known to be associated with cancer progression, maintenance of stemness, and poor prognosis. OTS167, a MELK kinase inhibitor, shows potent growth-suppressive effect on human tumors in a xenograft model, but the detailed mode of action has n...
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| Publicado no: | Oncotarget |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Impact Journals LLC
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4951280/ https://ncbi.nlm.nih.gov/pubmed/26918358 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7685 |
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